Article
  • Synthesis of Star-shaped Poly(ε-caprolactone) and Its Application to Drug Delivery Material
  • Won Taek Lim* and Young Soo Ko*, **†

  • *Department of Future Convergence Engineering, Kongju National University, Cheonan 31080, Korea
    **Department of Chemical Engineering, Kongju National University, Cheonan 31080, Korea

  • Star형 Poly(ε-caprolactone) 합성과 약물 전달체로응용
  • 임원택* · 고영수*, **†

  • *공주대학교 미래융합공학과, **공주대학교 화학공학과

  • Reproduction, stored in a retrieval system, or transmitted in any form of any part of this publication is permitted only by written permission from the Polymer Society of Korea.

References
  • 1. Boudoulas, K. D.; Triposkiadis, F.; Stefanadis, C.; Boudoulas, H.; Dr. Hon. The Endlessness Evolution of Medicine, Continuous Increase in Life Expectancy and Constant Role of the Physician. Hellenic J. Cardiol. 2017, 58, 322-330.
  •  
  • 2. Park, J.; Ye, M.; Park, K. Biodegradable Polymers for Microencapsulation of Drugs. Molecules 2005, 10, 146-161.
  •  
  • 3. Hwang, T. H.; Kim, J. B.; Yang, D. S.; Park, Y.; Ryu, W. H. Targeted Electrohydrodynamic Printing for Micro-reservoir Drug Delivery Systems. J. Micromech. Microeng. 2013, 23, 1-9.
  •  
  • 4. Freiberg, S.; Zhu, X. X.Polymer Microspheres for Controlled Drug Release. Int. J. Pharm. 2004, 282, 1-18.
  •  
  • 5. Altman, P. A. Catheter Drug Delivery System and Method for use. US patent 6,726,662 B2, 2004.
  •  
  • 6. Masood, F. Polymeric Nanoparticles for Targeted Drug Delivery System for Cancer Therapy. Mater. Sci. Eng., C 2016, 60, 569-578.
  •  
  • 7. Jalil, R.; Nixon, J. R. Biodegradable Poly(lactic acid) and Poly(lactide-co-glycolide) Microcapsules: Problems Associated with Preparative Techniques and Release Properties. J. Microencapsulation 1990, 7, 297-325.
  •  
  • 8. Shi, C.; Feng, S.; Liu, X.; Feng, X.; Fu, D. A Novel Study on the Mechanisms of Drug Release in PLGA-mPEG Microspheres with Fluorescent Drug. J. Biomater. Sci. Polym. Ed. 2016, 27, 854-864.
  •  
  • 9. Cui, Y.; Ma, X.; Tang, X.; Luo, Y. Synthesis, Characterization, and Thermal Stability of Star-shaped Poly(ε-caprolactone) with Phosphazene Core. Eur. Polym. J. 2004, 40, 299-305.
  •  
  • 10. Chen, D. R.; Bei, J. Z.; Wang, S. G. Polycaprolactone Microparticles and Their Biodegradation. Polym. Degrad. Stab. 2000, 47, 455-459.
  •  
  • 11. Ray, A. M. L.; Gautier, H.; Laty, M. K.; Daculsi, G.; Merie, C.; Jacqueline, C.; Hamel, A.; Caillon, J. In vitro and in vivo Bactericidal Activities of Vancomycin Dispersed in Porous Biodegradable Poly(e-caprolactone) Microparticles. Antimicrob. Agents Chemother. 2005, 49, 3025-3027.
  •  
  • 12. Danafar, H. MPEG-PCL Copolymeric Nanoparticles in Drug Delivery Systems. Cogent Med. 2016, 3, 1142411.
  •  
  • 13. Zhang, H.; Cui, W.; Bei, J.; Wang, S. Preparation of Poly(Lactide-co-glycolide-co-caprolactone) Nanoparticles and Their Degradation Behaviour in Aqueous Solution. Polym. Degrad. Stab. 2006, 91, 1929-1936.
  •  
  • 14. Wang, F.; Bronich, T. K.; Kabanov, A. V.; Rauh, R. D.; Roovers, J. Evaluation of a Star Amphiphilic Block Copolymer from Poly(ε-caprolactone) and Poly(ethylene glycol) as a Potential Drug Delivery Carrier. Bioconjugate Chem. 2005, 16, 197-405.
  •  
  • 15. Zhou, S.; Deng, X.; Yang, H. Biodegradable Poly(e-caprolactone)-poly(Ethylene glycol) Block Copolymers: Characterization and Their Use as Drug Carriers for a Controlled Delivery System. Biomaterials 2003, 24, 3563-3570.
  •  
  • 16. Labet, M.; Thielemans, W. Ynthesis of Polycaprolactone: a Review. Chem. Soc. Rev. 2009, 38, 3484-3504.
  •  
  • 17. Huang. J.; Yang. S. Studying the Miscibility and Thermal Behavior of Polybenzoxazine/Poly(ε-Caprolactone) Blends Using DSC, DMA, and Solid State 13C NMR Spectroscopy. Polymer 2005, 46, 8068-8078.
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2020 Impact Factor : 0.493
  • Indexed in SCIE

This Article

  • 2021; 45(5): 742-747

    Published online Sep 25, 2021

  • 10.7317/pk.2021.45.5.742
  • Received on Apr 26, 2021
  • Revised on Jun 7, 2021
  • Accepted on Jun 24, 2021

Correspondence to

  • Young Soo Ko
  • *Department of Future Convergence Engineering, Kongju National University, Cheonan 31080, Korea
    **Department of Chemical Engineering, Kongju National University, Cheonan 31080, Korea

  • E-mail: ysko@kongju.ac.kr