Article
  • Influence of Polycaprolactone/Collagen Ratio and Microstructure of Fibrous Membranes on Mechanical Properties and Anti-Platelet Properties

  • Jia-Shuai Zhang*,#, Hui-Lin Mo*,#, Shun-Yang Shen*,#, Du-Han Zhang*, Wei Zhang*, **,† , Yu Ren*, **,† , and Mei-Xian Li*, **,†

  • *School of Textile and Clothing, Nantong University, Nantong 226019, China
    **National and Local Joint Engineering Research Center of Technical Fiber Composites for Safety and Protection, Nantong University, Nantong 226019, China

  • Polycaprolactone/Collagen 비율과 섬유 막의 미세 구조가 기계적 특성 및 항혈소판 특성에 미치는 영향 연구

  • Reproduction, stored in a retrieval system, or transmitted in any form of any part of this publication is permitted only by written permission from the Polymer Society of Korea.

References
  • 1. Baranwal, J.; Barse, B.; Fais, A.; Delogu, G. L.; Kumar, A. Biopolymer: A Sustainable Material for Food and Medical Applications. Polymers 2022, 14, 983.
  •  
  • 2. Kovylin, R. S.; Aleynik, D. Y.; Fedushkin, I. L. Modern Porous Polymer Implants: Synthesis, Properties, and Application. Polym. Sci. Ser. C 2021, 63, 29-46.
  •  
  • 3. Jurak, M.; Wiacek, A. E.; Ladniak, A.; Przykaza, K.; Szafran, K. What Affects the Biocompatibility of Polymers? Adv. Colloid Interface Sci. 2021, 294, 102451.
  •  
  • 4. Xu, L. C.; Li, Z. J.; Tian, Z. C.; Chen, C.; Allcock, H. R.; Siedlecki, C. A. A New Textured Polyphosphazene Biomaterial with Improved Blood Coagulation and Microbial Infection Responses. Acta Biomater. 2018, 67, 87-98.
  •  
  • 5. Bruzauskaite, I.; Bironaite, D.; Bagdonas, E.; Bernotiene, E. Scaffolds and Cells for Tissue Regeneration: Different Scaffold Pore Sizes-Different Cell Effects. Cytotechnology 2016, 68, 355-369.
  •  
  • 6. Backes, E. H.; Harb, S. V.; Beatrice, C. A. G.; Shimomura, K. M. B.; Passador, F. R.; Costa, L. C.; Pessan, L. A. Polycaprolactone Usage in Additive Manufacturing Strategies for Tissue Engineering Applications: A Review. J. Biomed. Mater. Res. B Appl. Biomater. 2022, 110, 1479-1503.
  •  
  • 7. Jeong, Y.; Lee, D. Y. Mechanical Properties and Biocompatibility of Electrospun Poly(epsilon-caprolactone)/Gelatin Scaffolds Loaded with Cellulose Fiber. Polym. Korea 2022, 46, 837-842.
  •  
  • 8. Majidnia, E.; Ahmadian, M.; Salehi, H.; Amirpour, N. Development of An Electrospun Poly(ε-caprolactone)/Collagen-Based Human Amniotic Membrane Powder Scaffold for Culturing Retinal Pigment Epithelial Cells. Sci. Rep. 2022, 12, 6469.
  •  
  • 9. Yin, H. M.; Li, X.; Wang, P.; Ren, Y.; Liu, W.; Xu, J. Z.; Li, J. H.; Li, Z. M. Role of HA and BG in Engineering Poly(epsilon-caprolactone) Porous Scaffolds for Accelerating Cranial Bone Regeneration. J. Biomed. Mater. Res. Part A 2019, 107, 654-662.
  •  
  • 10. Shi, J.; Chen, S. Y.; Wang, L. N.; Zhang, X. Y.; Gao, J. C.; Jiang, L.; Tang, D.; Zhang, L.; Midgley, A.; Kong, D. L. et al. Rapid Endothelialization and Controlled Smooth Muscle Regeneration by Electrospun Heparin-Loaded Polycaprolactone/Gelatin Hybrid Vascular Grafts. J. Biomed. Mater. Res. Part B 2019, 107, 2040-2049.
  •  
  • 11. Nazeer, M. A.; Yilgor, E.; Yilgor, I. Electrospun Polycaprolactone/Silk Fibroin Nanofibrous Bioactive Scaffolds for Tissue Engineering Applications. Polymer 2019, 168, 86-94.
  •  
  • 12. Baburaj, M. S.; Veeran, M. G.; Painuly, D.; Sreelekshmi, S.; Aprem, A. S. Fabrication and Characterisation of Polycaprolactone/Gelatin/Chitosan (PCL/GEL/CHI) Electrospun Nano-Membranes for Wastewater Purification. Desalination 2023, 563, 116709.
  •  
  • 13. Jang, Y.; Jeong, Y.; Lee, D. Y. Double-Layer Wound Dressing Consisting of an Upper Layer of Robust Polyurethane/Polycaprolactone and a Lower Layer of Biodegradable Polycaprolactone/Gelatin/Cellulose. Polym. Korea 2023, 47, 151-156.
  •  
  • 14. Ji, W.; Yang, F.; Seyednejad, H.; Chen, Z.; Hennink, W. E.; Anderson, J. M.; van den Beucken, J.; Jansen, J. A. Biocompatibility and Degradation Characteristics of PLGA-Based Electrospun Nanofibrous Scaffolds with Nanoapatite Incorporation. Biomaterials 2012, 33, 6604-6614.
  •  
  • 15. Shenoy, M.; Abdul, N. S.; Qamar, Z.; Bahri, B. M. A.; Al Ghalayini, K. Z. K.; Kakti, A. Collagen Structure, Synthesis, and Its Applications: A Systematic Review. Cureus 2022, 14, e24856.
  •  
  • 16. Guo, Y. Y.; Cheng, N. Q.; Sun, H. X.; Hou, J. N.; Zhang, Y. C.; Wang, D.; Zhang, W.; Chen, Z. Y. Advances in the Development and Optimization Strategies of the Hemostatic Biomaterials. Front. Bioeng. Biotechnol. 2023, 10, 1062676.
  •  
  • 17. Ghomi, E. R.; Nourbakhsh, N.; Kenari, M. A.; Zare, M.; Ramakrishna, S. Collagen-Based Biomaterials for Biomedical Applications. J. Biomed. Mater. Res. Part B 2021, 109, 1986-1999.
  •  
  • 18. Lu, X. J.; Zou, H.; Liao, X. K.; Xiong, Y.; Hu, X. Y.; Cao, J.; Pan, J. Q.; Li, C. R.; Zheng, Y. Y. Construction of PCL-Collagen @PCL@PCL-Gelatin Three-Layer Small Diameter Artificial Vascular Grafts by Electrospinning. Biomed. Mater. 2023, 18, 015008.
  •  
  • 19. Kim, M. S.; Kim, Y. J. Polycaprolactone Composite Membranes Containing Polyphenol-Loaded Hydroxyapatite Nanoparticles for Bone Regeneration. Polym. Korea 2019, 43, 337-345.
  •  
  • 20. Zhao, P.; Chen, W.; Feng, Z.; Liu, Y.; Liu, P.; Xie, Y.; Yu, D. G. Electrospun Nanofibers for Periodontal Treatment: A Recent Progress. Int. J. Nanomed. 2022, 17, 4137-4162.
  •  
  • 21. Hemamalini, T.; Dev, V. R. G. Comprehensive Review on Electrospinning of Starch Polymer for Biomedical Applications. Int. J. Biol. Macromol. 2018, 106, 712-718.
  •  
  • 22. Kai, D.; Liow, S. S.; Loh, X. J. Biodegradable Polymers for Electrospinning: Towards Biomedical Applications. Mater. Sci. Eng. C-Mater. Biol. Appl. 2014, 45, 659-670.
  •  
  • 23. Li, Q.; Wang, X. L.; Lou, X. X.; Yuan, H. H.; Tu, H. B.; Li, B. Y.; Zhang, Y. Z. Genipin-crosslinked Electrospun Chitosan Nanofibers: Determination of Crosslinking Conditions and Evaluation of Cytocompatibility. Carbohydr. Polym. 2015, 130, 166-174.
  •  
  • 24. Yang, Z. H.; Wu, G. F. Effects of Soft Segment Characteristics on the Properties of Biodegradable Amphiphilic Waterborne Polyurethane Prepared by A Green Process. J. Mater. Sci. 2020, 55, 3139-3156.
  •  
  • 25. Gümüsderelioglu, M.; Dalkiranoglu, S.; Aydin, R. S. T.; Çakmak, S. A Novel Dermal Substitute Based on Biofunctionalized Electrospun PCL Nanofibrous Matrix. J. Biomed. Mater. Res. Part A 2011, 98A, 461-472.
  •  
  • 26. Lee, J. J.; Yu, H. S.; Hong, S. J.; Jeong, I.; Jang, J. H.; Kim, H. W. Nanofibrous Membrane of Collagen-polycaprolactone for Cell Growth and Tissue Regeneration. J. Mater. Sci. - Mater. Med. 2009, 20, 1927-1935.
  •  
  • 27. Jokinen, V.; Kankuri, E.; Hoshian, S.; Franssila, S.; Ras, R. H. A. Superhydrophobic Blood-Repellent Surfaces. Adv. Mater. 2018, 30, 1705104.
  •  
  • 28. Lenz-Habijan, T.; Bhogal, P.; Peters, M.; Bufe, A.; Moreno, R. M.; Bannewitz, C.; Monstadt, H.; Henkes, H. Hydrophilic Stent Coating Inhibits Platelet Adhesion on Stent Surfaces: Initial Results In Vitro. Cardiovasc. Interv. Radiol. 2018, 41, 1779-1785.
  •  
  • 29. Farndale, R. W. Collagen-induced platelet activation. Blood Cells Mol. Dis. 2006, 36, 162-165.
  •  
  • 30. Nuyttens, B. P.; Thijs, T.; Deckmyn, H.; Broos, K. Platelet Adhesion to Collagen. Thromb. Res. 2011, 127, S26-S29.
  •  
  • 31. Malikmammadov, E.; Tanir, T. E.; Kiziltay, A.; Hasirci, V.; Hasirci, N. PCL and PCL-Based Materials in Biomedical Applications. J. Biomater. Sci.-Polym. Ed. 2018, 29, 863-893.
  •  
  • 32. Kuppan, P.; Sethuraman, S.; Krishnan, U. M. PCL and PCL-Gelatin Nanofibers as Esophageal Tissue Scaffolds: Optimization, Characterization and Cell-Matrix Interactions. J. Biomed. Nanotechnol. 2013, 9, 1540-1555.
  •  
  • 33. Son, S.; Choi, J. E.; Cho, H.; Kang, D.; Lee, D. Y.; Kim, J. T.; Jang, J. W. Synthesis and Characterization of Porous Poly(ε-caprolactone)/Silica Nanocomposites. Polym. Korea 2015, 39, 323-328.
  •  
  • 34. Ma, W. X.; Wang, L. M.; Zhang, Q. L.; Dong, X. Y.; Zhu, T. H.; Lu, S. Y. Electrospun PCL/Collagen Hybrid Nanofibrous Tubular Graft Based on Post-Network Bond Processing for Vascular Substitute. Biomater. Adv. 2022, 139, 213031.
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2022 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2024; 48(1): 20-26

    Published online Jan 25, 2024

  • 10.7317/pk.2024.48.1.20
  • Received on Aug 8, 2023
  • Revised on Oct 24, 2023
  • Accepted on Nov 13, 2023

Correspondence to

  • Wei Zhang*, ** , Yu Ren*, ** , and Mei-Xian Li*, **

  • *School of Textile and Clothing, Nantong University, Nantong 226019, China
    **National and Local Joint Engineering Research Center of Technical Fiber Composites for Safety and Protection, Nantong University, Nantong 226019, China

  • E-mail: zhangwei@ntu.edu.cn, ren.y@ntu.edu.cn,