Article
  • Synthesis and Characteristics of Trimethylsilyl Chitin
  • Suh SB, Kim SJ, Lee YM, Kim JJ
  • 트리메틸실릴 키틴의 합성과 특성
  • 서상봉, 김선정, 이영무, 김재진
Abstract
Trimethylsilyl chitin(TMSC) was synthesize by chemically introducting silyl groups on chitin. FT-IR and solid state CP/MAS13C-NMR data show that silyl group has been introduced at the C-6 position of the glucosamin unit of chitin. The solubility of trimethylsilyl chitin film in solvents was investigated. From the solubility measurements it was shown that trimethylsilyl chitin was better soluble or swollen in some solvents than that chitin was. The biodegradation of TMSC by Iysozyme was investigated in vitro in pseudo-extracellular fluid. The results showed that the weight loss and the decrease in tensile strength were more severe in human bile at pH 6.7 than in extracellular fluid of pH 7.4 or human pancreatic juice of pH 8.2.

키틴에 실릴기를 도입시킨 트리메틸실릴 키틴(TMSC)을 합성하였다. FT-IR과 고체 CP/MAS 13C-NMR으로 글루코사민 단위의 6번 탄소 위치에 실릴기가 치환된 것을 확인하였다. TMSC 필름을 제조하여 유기용매에 대한 용해성을 실험한 결과, 실험에 사용된 유기응매들에서 키틴보다 팽윤성과 용해성이 증가되는 결과를 얻었다. 생분해성 실험은 in vitro하에서 생체조건과 유사한 체액을 제조하여 라이소자임효소를 넣어 행하였으며, 그 결과 pH 7.4의 체액 범위와 pH 8.2의 소화장액 범위에서 보다는 pH 6.7의 담즙액 범위에서 무게 감소율과 인장강도의 감소율이 크게 나타났다.

Keywords: Trimethylsilyl chitin; biodegradation; solubility

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  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 1994; 18(6): 906-913

    Published online Nov 25, 1994