• Evaluation of Thermal Stability and Cytotoxicity of Polyvinyl Chloride/MgAl-Layered Double Hydroxide Composite Based on Ca-Zn Stabilizer
  • Young Seob Jong, Jae Hyung Park*,† , Ji Eun Lee*, and Eun-Soo Park†

  • Intechnology Co., Ltd., 861-46, Poseungjangan-ro, Jang-an-ri, Jangan-myeon, Hwaseong-si, Gyeonggi-do 18586, Korea
    *Fusion Material Research Group, Korea Institute of Materials Convergence Technology, Busan 47154, Korea

  • 칼슘-아연 안정제를 기반으로 한 폴리염화비닐/MgAl-층상이중수산화물 복합체의 열 안정성 및 세포 독성 평가
  • 정영섭 · 박재형*,† · 이지은* · 박은수†

  • (주)인테크놀로지, *한국소재융합연구원 융합소재연구단

  • Reproduction, stored in a retrieval system, or transmitted in any form of any part of this publication is permitted only by written permission from the Polymer Society of Korea.

References
  • 1. Asawakosinchai, A.; Jubsilp, C.; Mora, P.; Rimdusit, S. Organic Heat Stabilizers for Polyvinyl Chloride (PVC): A Synergistic Behavior of Eugenol and Uracil Derivative. J Mater. Eng. Perform. 2017, 26, 4781-4788.
  •  
  • 2. Jubsilp, C.; Asawakosinchai, A.; Mora, P.; Saramas, D.; Rimdusit, S. Effects of Organic Based Heat Stabilizer on Properties of Polyvinyl Chloride for Pipe Applications: A Comparative Study with Pb and CaZn Systems. Polymers 2022, 14, 133.
  •  
  • 3. Close, L. G.; Gilbert, R. D.; Forne, R. E. Poly(Vinyl Chloride) Degradation-A Review. Polym-Plast. Technol. Eng. 1977, 8, 177-198.
  •  
  • 4. Arkış, E.; Balköse, D. Thermal Stabilisation of Poly(vinyl chloride) by Organotin Compounds. Polym. Degrad. Stab. 2005, 88, 46-51.
  •  
  • 5. Sombatsompop, N.; Taptim, K.; Chaochanchaikul, K.; Thongpin, C. Improvement of Structural and Thermal Stabilities of PVC and Wood/PVC Composite by Zn and Pb Stearates, and Zeolite. J. Macromol. Sci. Part A-Pure Appl. Chem. 2008, 45, 534-541.
  •  
  • 6. Li, D.; Zhou, M.; Xie, L.; Yu, X.; Yu, Y.; Ai, H.; Tang, S. Synergism of Pentaerythritol-zinc with β-diketone and Calcium Stearate in Poly(vinyl chloride) Thermal Stability. Polym. J. 2013, 45, 775-782.
  •  
  • 7. Mochane, M. J.; Magagula, S. I.; Sefadi, J. S.; Sadiku, E. R.; Mokhena, T. C. Morphology, Thermal Stability, and Flammability Properties of Polymer-Layered Double Hydroxide (LDH) Nanocomposites: A Review. Crystals 2020, 10, 612.
  •  
  • 8. Yu, G.; Zhou, Y.; Yang, R.; Wang, M.; Shen, L.; Li Y.; Xue, N.; Guo, X.; Ding, W.; Peng, L. Dehydration and Dehydroxylation of Layered Double Hydroxides: New Insights from Solid-State NMR and FT-IR Studies of Deuterated Samples. J. Phys. Chem. C 2015, 119, 12325-12334.
  •  
  • 9. Du, L.; Qu, B.; Zhang, M. Thermal Properties and Combustion Characterization of nylon 6/MgAl-LDH Nanocomposites via Organic Modification and Melt Intercalation. Polym. Degrad. Stab. 2007, 92, 497-502.
  •  
  • 10. Shen, G.; Zhao, Y.; Ma, M.; Wang, Y.; Hao, X.; Yuan, G. Enhancing the Initial Whiteness and Long‐Term Thermal Stability of Polyvinyl Chloride by Utilizing Layered Double Hydroxides with Low Surface Basicity. Polymers 2023, 15, 1043.
  •  
  • 11. Zhang, J.; Xu, B.; Wang, H.; Jin, F.; Dai, J.; Fu, S. Efficient Thermo-Stability and Smoke-Suppression Properties of La Doping Mg-Al LDHs on PVC Nanocomposites. Mater. Plast. 2020, 57, 297-308.
  •  
  • 12. Cavani, F.; Trifiro, F.; Vaccari, A. Hydrotalcite-type Anionic Clays: Preparation, Properties and Applications. Catal. Today 1991, 11, 173-301.
  •  
  • 13. Khan, A. I.; O’Hare, D. Intercalation Chemistry of Layered Double Hydroxides: Recent Developments and Applications. J. Mater. Chem. 2002, 12, 3191-3198.
  •  
  • 14. Singh, M.; Singh, R. K.; Singh, S. K.; Mahto, S. K.; Misra, N. In Vitro Biocompatibility Analysis of Functionalized Poly(vinyl chloride)/layered Double Hydroxide Nanocomposites. RSC Adv. 2018, 8, 40611-40620.
  •  
  • 15. Beltrami, R.; Colombo, M.; Rizzo, K.; Cristofaro, A. D.; Poggio, C.; Pietrocola, G. Cytotoxicity of Different Composite Resins on Human Gingival Fibroblast Cell Lines. Biomimetics 2021, 6, 26.
  •  
  • 16. Choi, S. J.; Oh, J. M.; Choy, J. H. Safety Aspect of Inorganic Layered Nanoparticles: Size-Dependency In Vitro and In Vivo. J. Nanosci. Nanotechnol. 2008, 8, 5297-5301
  •  
  • 17. Abd El-Ghaffar, M. A.; Youssef, E. A. M.; Afify, M. F. High Performance Metal Stearates Thermal Stabilizers for Poly Vinyl Chloride. Int. J. Petrochem. Sci. Eng. 2019, 4, 162-168.
  •  
  • 18. Lévai, G. Y.; Ocskay, G. Y.; Nyitrai, Z. S. Effect of the Dissociation of Barium and Cadmium Stearates on the Heat Stabilization of PVC. Polym. Degrad. Stab. 1994, 43, 159-164.
  •  
  • 19. Phillips, J.; Weldhagen, M.; Mhlabeni, T.; Radebe, L.; Ramjee, S.; Wesley-Smith, J.; Atanasova, M.; Focke, W. W. Thermal Characterisation of Metal Stearate Lubricant Mixtures for Polymer Compounding Applications. Thermochimica Acta. 2021, 699, 178906.
  •  
  • 20. Wang, X.; Di, C.; Wang, T. Effect of Different Tin Neodecanoate and Calcium-zinc Heat Stabilizers on the Thermal Stability of PVC. e-Polymers 2023, 23, 20230029.
  •  
  • 21. Choi, E. M. Cytotoxicity (MTT) Evaluation of Dental Instruments Made of Polymers. J. Korea Converg. Soc. 2021, 12, 187-195.
  •  
  • 22. Jenke, D. R. Extraction of Stearate Salts from Plastic Materials Used in Pharmaceutical Applications. PDA J. Pharm. Sci. Technol. 2010, 64, 200-210.
  •  
  • 23. de Kruijf, N.; Rijk, R. The Suitability of Alternative Fatty Food Simulants for Overall Migration Testing Under Both Low- and High-temperature Test Conditions. Food. Addit. Contam. 1997, 14, 775-789.
  •  
  • 24. Forano, C.; Bruna, F.; Mousty, C.; Prevot, V. Interactions Between Biological Cells and Layered Double Hydroxides: Towards Functional Materials. Chem. Rec. 2018, 18, 1-18.
  •  
  • 25. Berridge, M. V.; Herst, P. M.; Tan, A. S. Tetrazolium Dyes as Tools in Cell Biology: New Insights Into Their Cellular Reduction. Biotechnol. Annu. Rev. 2005, 11, 127-152.
  •  
  • 26. Kamiloglu, S.; Sari, G.; Ozdal, T.; Capanoglu, E. Guidelines for Cell Viability Assays. Food Frontiers 2020, 1, 332-349.
  •  
  • 27. Strober, W. Trypan Blue Exclusion Test of Cell Viability. Curr. Protoc. Immunol. 2015, 111, A3.B.1-A3.B.3.
  •  
  • 28. Benavides, R.; Edge, M.; Allen, N. S.; Te´llez, M. M. Stabilization of Poly(vinyl chloride) with Preheated Metal Stearates and Costabilizers. I. Use of a β-Diketone. J. Appl. Polym. Sci. 1998, 68, 1-10.
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2025 Impact Factor : 1.0
  • Indexed in SCIE

This Article

  • 2026; 50(5): 726-735

    Published online Sep 25, 2026

  • 10.7317/pk.2026.50.5.726
  • Received on May 15, 2026
  • Revised on Jun 15, 2026
  • Accepted on Jun 16, 2026

Correspondence to

  • Jae Hyung Park*, Eun-Soo Park
  • Intechnology Co., Ltd., 861-46, Poseungjangan-ro, Jang-an-ri, Jangan-myeon, Hwaseong-si, Gyeonggi-do 18586, Korea
    *Fusion Material Research Group, Korea Institute of Materials Convergence Technology, Busan 47154, Korea

  • E-mail: park1360@hanmail.net, t2phage@hitel.net